Randomized Trialhigh evidence
Prehospital Resuscitation with Type O Whole Blood for Trauma and Hemorrhage.
The New England journal of medicine·June 18, 2026·PMID 42150044
Why it mattersPrehospital transfusion is critical for trauma, but the optimal product remains debated. This large trial provides high-level evidence that whole blood does not reduce mortality compared to components, informing resource allocation and protocol development for emergency medical services.
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