Randomized Trialhigh evidence

Dapagliflozin and Acute Kidney Injury Following Cardiac Surgery: A Randomized Clinical Trial.

JAMA·July 30, 2026·PMID 42530910

Why it matters

AKI after cardiac surgery is common and lacks proven pharmacologic prevention. This trial provides robust evidence that a short course of dapagliflozin significantly lowers AKI risk, offering a potential new strategy for perioperative renal protection.

Infographic summary of Dapagliflozin and Acute Kidney Injury Following Cardiac Surgery: A Randomized Clinical Trial.
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