Meta-Analysishigh evidence
Updated Meta-Analysis of Left Atrial Appendage Closure Versus Oral Anticoagulation to Prevent Stroke in Atrial Fibrillation.
Stroke·November 1, 2026·PMID 42817893
Why it mattersFor cardiologists and internists managing atrial fibrillation, this updated analysis clarifies that LAAC reduces bleeding but may not match anticoagulation for ischemic stroke prevention, especially in standard-risk patients.
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