Randomized Trialhigh evidence
Effect of Screening with Multicancer Early-Detection Test on Late-Stage Cancer Diagnosis.
The New England journal of medicine·September 22, 2026·PMID 42776074
Why it mattersMulticancer early-detection blood tests are being marketed for cancer screening, but their clinical utility remains unproven. This large trial provides high-quality evidence that adding such testing to usual care did not reduce late-stage cancer diagnoses overall, tempering enthusiasm for widespread adoption without further data.
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