Cohort Studymoderate evidence
Microvascular Resistance Reserve and Outcomes in Angina and Nonobstructive Coronary Artery Disease.
JAMA cardiology·November 1, 2026·PMID 42967827
Why it mattersCoronary microvascular dysfunction is common in ANOCA, yet its long-term prognostic significance remains unclear. This study suggests that MRR-defined CMD may not predict major adverse events but is linked to persistent angina, informing risk stratification and symptom management in this challenging population.

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