Case-Controlmoderate evidence
Gut Microbiome in Depression with and without REM Sleep Behavior Disorder.
Molecular psychiatry·July 23, 2026·PMID 42493609
Why it mattersMDD with comorbid RBD may represent a distinct subtype with underlying α-synucleinopathy risk, and gut microbiome signatures could aid in stratifying psychiatric patients for neurodegenerative vulnerability.

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