Meta-Analysismoderate evidence
Contemporary nutritional strategies in severe burn care: A systematic review and meta-analysis on glutamine supplementation, vitamin C, and macronutrient ratios.
Burns : journal of the International Society for Burn Injuries·October 6, 2026·PMID 42868688
Why it mattersSevere burns induce hypermetabolism and immune dysfunction, making nutritional support a key therapeutic target. This review clarifies that routine glutamine monotherapy lacks benefit and high-dose vitamin C is harmful, while a high-carbohydrate, low-fat approach shows early promise for wound healing and sepsis reduction.
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