Cohort Studyhigh evidence
Exploring high priority potentially inappropriate prescribing cascades in older adults: population level retrospective cohort study.
BMJ (Clinical research ed.)·September 10, 2026·PMID 42727946
Why it mattersPrescribing cascades—where a drug is used to treat side effects of another drug—are common and often preventable in older adults. This study provides a prioritized list of 24 high-impact cascades, enabling clinicians to recognize and interrupt harmful medication sequences during medication review.

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