Cohort Studyhigh evidence
DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease.
Nature aging·August 1, 2025·PMID 40595015
Why it mattersDunedinPACNI offers a practical, single-scan tool to quantify biological aging in the brain, which could help pain specialists identify patients at higher risk for age-related functional decline, multimorbidity, and poor outcomes, potentially guiding more proactive management.

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