Randomized Trialhigh evidence
4% Tetrasodium EDTA to Prevent Central Venous Access Device-Associated Complications: A Randomized Clinical Trial.
JAMA·June 23, 2026·PMID 42150112
Why it mattersCentral venous access device complications are common in the ICU, leading to morbidity, delays, and costs. A locking solution that reduces occlusions and potentially infections offers a practical, low-risk intervention to improve catheter function and patient safety.

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