Randomized Trialhigh evidence
Gliclazide Enhances Exercise Performance and Recovery of Muscle Strength in Healthy Trained Individuals: A Randomized Controlled Trial.
European journal of sport science·April 1, 2026·PMID 41818607
Why it mattersFor sports medicine, PM&R, and pain specialists, this study highlights that a sulfonylurea can alter exercise performance and recovery metrics even in healthy trained adults, but at the cost of clinically relevant hypoglycemia risk. It is more notable as a safety and mechanistic signal than as a practice-ready recovery strategy.
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