Randomized Trialhigh evidence
Pro-cognitive effects of 5-HT4 receptor agonism in individuals with remitted depression.
Psychological medicine·June 15, 2026·PMID 42290157
Why it mattersCognitive deficits often persist in remitted depression and lack effective treatments. This study provides early evidence that 5-HT4 receptor agonism may enhance cognition in this population, offering a potential novel target for addressing residual cognitive symptoms.
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