Meta-Analysishigh evidence
Preoperative Methicillin-Resistant Staphylococcus aureus Colonization and Risk of Periprosthetic Joint Infection after Total Joint Arthroplasty: A Systematic Review and Meta-Analysis.
The Journal of arthroplasty·July 28, 2026·PMID 42520992
Why it mattersOrthopedic surgeons performing total joint arthroplasty need to recognize that standard MRSA decolonization protocols may not fully mitigate infection risk in colonized patients, underscoring the need for enhanced prophylaxis and surveillance.

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