Randomized Trialhigh evidence
Digoxin in Patients With Symptomatic Rheumatic Heart Disease: A Randomized Clinical Trial.
JAMA·May 10, 2026·PMID 42106990
Why it mattersRheumatic heart disease remains a major global cause of heart failure, yet evidence for digoxin in this population has been absent. This trial provides the first randomized data supporting its efficacy and safety, directly informing management in regions where the disease is prevalent.
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