Randomized Trialhigh evidence
High-flow nasal oxygen therapy via a single-prong cannula interface during bronchoscopy in patients with acute respiratory failure: a two-center, open-label, randomized controlled trial.
Annals of intensive care·January 1, 2026·PMID 42179655
Why it mattersFlexible bronchoscopy in acute respiratory failure often worsens hypoxemia and can precipitate respiratory deterioration. This trial provides direct evidence that a simple modification—using HFNO via a single-prong cannula—reduces clinically meaningful escalations in respiratory support, including intubation, offering a practical strategy to improve procedural safety.
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