Randomized Trialhigh evidence
Left Atrial Appendage Closure or Anticoagulation for Atrial Fibrillation.
The New England journal of medicine·June 4, 2026·PMID 41910347
Why it mattersThis trial provides evidence that LAAC is a reasonable alternative to NOACs for stroke prevention in AF patients who are candidates for anticoagulation, offering similar efficacy with significantly less long-term bleeding.
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