Randomized Trialhigh evidence

Effect of S-Ketamine on Postoperative Delirium in Elderly Patients Undergoing Arthroplasty: A Randomized Controlled Trial.

Anesthesiology·January 1, 2026·PMID 41086424

Why it matters

Postoperative delirium is a common and serious complication in elderly arthroplasty patients, and this trial suggests S-ketamine may offer a protective effect when used in a neuraxial anesthesia setting, potentially improving perioperative outcomes.

Infographic summary of Effect of S-Ketamine on Postoperative Delirium in Elderly Patients Undergoing Arthroplasty: A Randomized Controlled Trial.
Visual abstract · MedLit

The papers that matter, first.

MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.

§

MedLit · Evidence, Distilled