Randomized Trialhigh evidence

Resuscitation From Out-of-Hospital Cardiac Arrest: When Is EtCO2 Reliably Associated With ROSC?

Circulation·July 14, 2026·PMID 42145111

Why it matters

EtCO2 monitoring is already standard during cardiac arrest, but clinicians lack guidance on how long to observe trends before interpreting prognostic value. This study provides specific time windows for when EtCO2 trajectories become reliably discriminatory, potentially aiding real-time decision-making during resuscitation.

Infographic summary of Resuscitation From Out-of-Hospital Cardiac Arrest: When Is EtCO2 Reliably Associated With ROSC?
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