Guidelinehigh evidence
Pharmacologic Treatment for Migraine Prevention in Adults Practice Guideline Recommendations: Report of the AAN Guidelines Subcommittee and the American Headache Society.
Neurology·October 13, 2026·PMID 42673560
Why it mattersMigraine prevention decisions are complex, especially in patients with comorbidities or special circumstances. This guideline synthesizes current evidence to help clinicians select appropriate preventive medications, balance benefits and harms, and tailor therapy to individual patient profiles.

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