Meta-Analysishigh evidence

Accuracy of type 2 inflammatory biomarkers to diagnose asthma in adults and children: a meta-analysis of 30 studies with prospective validation in an adult primary care cohort.

The Lancet. Respiratory medicine·September 15, 2026·PMID 42743935

Why it matters

Asthma diagnosis in primary care is often hindered by low bronchodilator reversibility and limited access to bronchial provocation testing. FeNO offers a practical, non-invasive biomarker that can rule in or rule out asthma with high predictive values, potentially streamlining diagnosis and reducing unnecessary referrals.

Infographic summary of Accuracy of type 2 inflammatory biomarkers to diagnose asthma in adults and children: a meta-analysis of 30 studies with prospective validation in an adult primary care cohort.
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