Meta-Analysismoderate evidence
Age-Specific Analysis of the Effects of Intermittent Fasting on Body Composition and Cardiometabolic Markers in Healthy Adults and Individuals with Overweight or Obesity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Nutrients·June 3, 2026·PMID 42280443
Why it mattersClinicians advising patients on intermittent fasting must consider age-specific risks and benefits, particularly lean mass loss and LDL-C increases, to tailor monitoring and adjunctive strategies like protein intake and resistance training.

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